BIOQUANT OSTEO

The BIOQUANT OSTEO software enables cutting-edge bone biology research in animal models. It supports both high-throughput automation and precise manual interaction for ASBMR standard bone histomorphometry. Unique tools simplify skeletal phenotyping, arthritis model assessment, help characterize cancer metastasis, aid in forensic anthropology, and quantify implant osseointegration.

BIOQUANT OSTEO 11.2 General Release Has Begun

Recent BIOQUANT OSTEO Citations

  • Chronic hyponatremia exacerbates multiple manifestations of senescence in male rats AuthorsJulia Barsony, Michaele B. Manigrasso, Qin Xu, Helen Tam and Joseph G. VerbalisAbstractThe syndrome of inappropriate antidiuretic hormone secretion (SIADH) is frequently responsible for chronic hyponatremia in the elderly due to age-related disruption of the inhibitory component of brain osmoregulatory mechanisms. Recent research has indicated that chronic hyponatremia is associated with gait disturbances, increased falls, and bone fragility in humans, and we have found that chronic hyponatremia causes increased bone resorption and reduced bone mineral density in young rats. In this study, we used a model of SIADH to study multi-organ consequences of chronic hyponatremia in aged rats. Sustained hyponatremia for 18 weeks caused progressive reduction of bone mineral density by DXA and decreased bone ...
    Posted Jan 10, 2012 6:46 AM by Nathanael Reveal
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BIOQUANT LIFE SCIENCE

The BIOQUANT LIFE SCIENCE software enables cutting edge bioscience research in animal models. It supports high-throughput immunofluorescence and immunohistochemistry, stereology, denstiometry, and 3D modeling. Primary applications include developmental neuroscience, traumatic brain/spinal cord injury, glaucoma, eye-movement disorders, cardiovascular disease and muscle disorders.
Learn more about BIOQUANT LIFE SCIENCE...
View the BIOQUANT Life Science 2011 Media Kit

BIOQUANT LIFE SCIENCE 11.2 General Release Has Begun

Recent BIOQUANT LIFE SCIENCE Citations

  • Delivery of VEGF using collagen-coated polycaprolactone scaffolds stimulates angiogenesis AuthorsShivani Singh, Benjamin M. Wu, James C. Y. DunnAbstractEstablishing sufficient vascularization in scaffold remains a challenge for tissue-engineering. To improve angiogenesis, we incorporated vascular endothelial growth factor (VEGF) in collagen-coating over the porous polycaprolactone (PCL) scaffolds. The release kinetics of loaded VEGF from collagen-coated PCL (col-PCL) scaffolds was same as from scaffolds without the collagen. The bioactivity of VEGF delivered by the col-PCL scaffolds was confirmed by human umbilical vein endothelial cell (HUVEC) proliferation and chorioallantoic membrane (CAM) assay. The col-PCL scaffolds were implanted subcutaneously in mice for 7 and 14 days. At day 7, vascularization within scaffolds loaded with VEGF was superior to that in the scaffolds without VEGF. However ...
    Posted Jan 13, 2012 6:45 AM by Nathanael Reveal
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