BIOQUANT OSTEO

The BIOQUANT OSTEO software enables cutting-edge bone biology research in animal models and human biopsy. It supports both high-throughput automation and precise manual interaction for ASBMR standard bone histomorphometry in digital histology and microCT. Unique tools simplify skeletal phenotyping, characterize arthritis models, help quantify cancer metastasis, measure chondrocyte proliferation, aid in forensic anthropology, and quantify implant osseointegration.

BIOQUANT OSTEO 16.1

http://osteo.bioquant.com/

Latest BIOQUANT OSTEO Citation

  • Rictor is required for optimal bone accrual in response to anti-sclerostin therapy in the mouse AuthorsWeiwei Sun, Yu Shi, Wen-Chih Lee, Seung-Yon Lee, Fanxin LongAbstractWnt signaling has emerged as a major target pathway for the development of novel bone anabolic therapies. Neutralizing antibodies against the secreted Wnt antagonist sclerostin (Scl-Ab) increase bone mass in both animal models and humans. Because we have previously shown that Rictor-dependent mTORC2 activity contributes to Wnt signaling, we test here whether Rictor is required for Scl-Ab to promote bone anabolism. Mice with Rictor deleted in the early embryonic limb mesenchyme (Prx1-Cre;Rictorf/f, hereafter RiCKO) were subjected to Scl-Ab treatment for 5 weeks starting at 4 months of age. In vivo micro–computed tomography (μCT) analyses before the treatment showed ...
    Posted Feb 1, 2016, 8:47 AM by Jon Hasfjord
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BIOQUANT LIFE SCIENCE

The BIOQUANT LIFE SCIENCE software enables cutting edge bioscience research in animal models and human biopsy. It supports high-throughput immunofluorescence and immunohistochemistry, stereology, densitometry, and 3D modeling. Primary applications include developmental neuroscience, traumatic brain/spinal cord injury, glaucoma, eye-movement disorders, cardiovascular disease and muscle disorders.

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BIOQUANT LIFE SCIENCE 15.5

http://lifescience.bioquant.com

Latest BIOQUANT LIFE SCIENCE Citation

  • Litter-of-origin trait effects on gilt development AuthorsJ. L. Vallet, J. A. Calderón-Díaz, K. J. Stalder, C. Phillips, R. A. Cushman, J. R. Miles, L. A. Rempel, G. A. Rohrer, C. A. Lents, B. A. Freking and D. J. NonnemanAbstractThe preweaning litter environment of gilts can affect subsequent development. In a recent experiment designed to test the effects of diet on gilt development, litter-of-origin traits including individual birth weights, immunocrits (a measure of colostrum intake), sow parity, number weaned, and individual weaning weights were collected for approximately 1,200 gilts that were progeny of approximately 300 sows. Subsequently, BW, LM area, and backfat were measured at 100 d of age and at 28-d intervals until slaughter (260 d of age ...
    Posted Feb 1, 2016, 8:25 AM by Jon Hasfjord
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