Using Feulgen staining to linearly stain DNA contained in cell nuclei, BIOQUANT calculates the genome size of a target species based on the genome size of a referent species.

In semi-thin sections with myelin specific staining, BIOQUANT automatically detects myelinated axons. Detection is based on color, shape, and size. Shape filters automatically exclude obliquely cut axons. 

The neonatal formation of new bone is driven in part by the rapid growth of uncalcified cartilage. Examination of cell proliferation patterns in chondrocytes can help shed light on this mechanism. There are several unique automated cell counting tools in BIOQUANT to accelerate this work.

Using the DAB chromagen, BIOQUANT identifies PCNA+ chondrocytes. Size and shape filters exclude non-specific staining. Using the counterstain, BIOQUANT identifies the other chondrocytes in the referent area.

Using automated tracing algorithms, BIOQUANT measures cross-sectional area in serially sectioned volumes of tissue. 

BIOQUANT Life Science includes the Stereology Toolkit. Stereology Grids provide an established set of tools for the stereological estimation of cell number. Stereology templates are provided for the Optical Fractionator Project, Lung Stereology, and Cavalieri Stereology.